The twerk phenotype was identified among N -ethyl- N -nitrosourea ENU -mutagenized G3 mice of the pedigree R, some of which exhibited ataxia Figure 1. Figure 2. Linkage mapping of the ataxia phenotype using a recessive model of inheritance. Manhattan plot shows -log10 P values Y-axis plotted against the chromosome positions of mutations X-axis identified in the G1 male of pedigree R Binary data are shown for single locus linkage analysis without consideration of G2 dam identity.
Individually-performed, chiefly but not exclusively by women,   dancers move by throwing or thrusting their hips back or shaking their buttocks , often in a low squatting stance. As a tradition shaped by local aid and pleasure clubs, block parties and second lines ,  the dance was central to "a historical situating of sissy bounce—bounce music as performed by artists from the New Orleans African-American community that [led to] a meteoric rise in popularity post-[ Hurricane Katrina after ]. The Oxford English Dictionary defines an 18th-century use of the word as a blend of "twist" and "jerk", which was reported by the BBC in conjunction with the black cultural context, but this seems to be an erroneous connection or a false cognate. Popular video-sharing channels such as YouTube amplified interest since the advent of digital social media platforms. In , the dance became a viral sensation beyond black culture. It became the number one "What is" Google search that year  as those outside the culture questioned the popularity of the dance.
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